Tick and flea treatment and infestation prevention for dogs 25.1 to 50.0 lbs., at least 8 weeks of age Fast-acting ingredients start killing Ixodes ricinus ticks and adult fleas in just 4 hours Kills 100% of fleas in 12 hours & stays effective throughout the entire month Easy to give your dog; no greasy, messy application Small, beef-flavored chewable tablet accepted by 100% of dogs tested (Karadzovska D, Chappell K, Coble S, et al. A randomized, controlled field study to assess the efficacy and safety of lotilaner flavored chewable tablets (Credelio) in eliminating fleas in client-owned dogs in the USA. Parasite Vector. 2017;10(1):528.)