No Setup needed. Just install new batteries and it is ready to use. Remote control with Display screen for VIZIO Home Theater Sound Bar Compatible with Vizio sound bar model as below: (1). VIZIO 42” 5.1 Home Theater Sound Bar S4251W-B4 S5430W-C2 Soundbar Remote Control 90.76G11.003 (XRS530) S4221W-C4 S4251w-B4 S4251W S3851W-C0 S4251W-C0 VIZIO 5.1 2.1 Sound Bar Vizio S5451w-C2 S5430W-C2B S5451WC2 S5451W-C2 S5451WC2NA S5451W-C2NA Soundbar Remote Control 90.76G11.003-R (XRS530) (2).54” 3.0 Home Theater Sound Bar S5430W-C2; (3). 42” 2.1 Home Theater Sound Bar S4221W-C4 Power Supply: 2 x 1.5V AAA Batteries (Not Included). Please use the brand new alkaline battery to have the display showing well. Remote control with Display screen for VIZIO Home Theater Sound Bar S4221W-C4 S4251W-B4 and more No Setup needed. Just install new batteries and it is ready to use. Compatible with Vizio sound bar model as below: (1). VIZIO 42” 5.1 Home Theater Sound Bar S4251W-B4 S5430W-C2 Soundbar Remote Control 90.76G11.003 (XRS530) S4221W-C4 S4251w-B4 S4251W S3851W-C0 S4251W-C0 VIZIO 5.1 2.1 Sound Bar Vizio S5451w-C2 S5430W-C2B S5451WC2 S5451W-C2 S5451WC2NA S5451W-C2NA Soundbar Remote Control 90.76G11.003-R (XRS530) (2).54” 3.0 Home Theater Sound Bar S5430W-C2 (3). 42” 2.1 Home Theater Sound Bar S4221W-C4 Power Supply: 2 x 1.5V AAA Batteries(Not Included)