NO ICE PACKS, EVER AGAIN! The FRIO wallet eliminates the need for ice packs. With no ice, your medication will not freeze - and your storage will be stress-free! WATER ACTIVATED COOLING - The FRIO evaporative cooler activates by simply soaking in water for 10-15 minutes - and then cools for 2-4 days. To re-activate simply soak again. THE SMALL FRIO IS IDEAL FOR CARRYING 4 INSULIN VIALS -FRIO comes in many different sizes to accommodate your medication needs. Not the right FRIO size? See the size guide below. TRAVEL SMART, TRAVEL FRIO - Jet set without limits! Enjoy stress free adventures with our travel insulin cooler. Get secure, on-the-go insulin storage without the fridge. TSA friendly. EMERGENCY PREPAREDNESS - Without the need for refrigeration or electricity, the FRIO is the ideal way to keep your critical medication cool and safe during a disaster. The FRIO provides you with freedom, convenience, and peace of mind!